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	LIPID Metabolites And Pathways Strategy

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Data

Experimental Results

Lipidomics Studies on Macrophages

• RAW 264.7 cells
  • Kdo2-lipid A Timecourse Experiments
  • Compactin/Kdo2-lipid A Timecourse Experiments

• Primary Macrophages
  • Thioglycolate-elicited peritoneal Macrophages
    • Microarray analysis of LPS responses of thioglycolate-elicited macrophages and counter-regulation by glucocorticoid receptor, PPARγ and LXR-specific ligands
    • Foam cell study with wild-type and LDLR(-/-) mice
    • Thioglycolate-elicited Macrophage Timecourse Experiments
    • Compare TGEM and BMDM cell Timecourse Experiments (0,6,24 hrs)
    • Compare TGEM and RAW cell Timecourse Experiments for sterols(full timecourse)
  • Bone marrow-derived Macrophages
    • Bone marrow-derived Macrophage Timecourse Experiments

Gene array data on Macrophages

• RAW 264.7 cells
  • Kdo2-lipid A Timecourse Experiments
  • Compactin/Kdo2-lipid A Timecourse Experiments

• Primary Macrophages
  • Thioglycolate-elicited Macrophages
    • Foam cell study with LDLR(-/-) and wild-type mice
    • Thioglycolate-elicited Macrophage Timecourse Experiments
  • Bone marrow-derived Macrophages
    • Bone marrow-derived Macrophage Timecourse Experiments

Integrated Pathways with heatmap data

• Kdo2-lipid A Timecourse Experiments
  • Sphingolipids
    • Tabular display
      Pathway display(N-acyl chain):C16;C18; C20;C22; C24:1;C24; C26:1;C26;
      Pathway display:All chain lengths
  • Eicosanoids
    • Tabular display
      Pathway display
  • Glycerolipids/Glycerophospholipids
    • Tabular display
      Pathway display(acyl chains): 32:0; 34:0; 34:1; 36:0; 36:1; 38:1; 38:4
  • Sterol lipids
    • Tabular display
      Pathway display