LMPD Database

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LMP004676

Record overview

LMPD IDLMP004676
Gene ID9197
SpeciesHomo sapiens (Human)
Gene Namesolute carrier family 33 (acetyl-CoA transporter), member 1
Gene SymbolSLC33A1
SynonymsACATN; AT-1; AT1; CCHLND; SPG42
Alternate namesacetyl-coenzyme A transporter 1
Chromosome3
Map Location3q25.31
SummaryThe protein encoded by this gene is required for the formation of O-acetylated (Ac) gangliosides. The encoded protein is predicted to contain 6 to 10 transmembrane domains, and a leucine zipper motif in transmembrane domain III. Defects in this gene have been reported to cause spastic paraplegia autosomal dominant type 42 (SPG42) in one Chinese family, but not in similar patients of European descent. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2010]
OrthologsView orthologs and multiple alignments for SLC33A1

Proteins

acetyl-coenzyme A transporter 1
Refseq ID:NP_001177921
Protein GI:300360496
UniProt ID:O00400
mRNA ID:NM_001190992
Length:549
RefSeq Status:REVIEWED
MSPTISHKDSSRQRRPGNFSHSLDMKSGPLPPGGWDDSHLDSAGREGDREALLGDTGTGDFLKAPQSFRAELSSILLLLFLYVLQGIPLGLAGSIPLILQ
SKNVSYTDQAFFSFVFWPFSLKLLWAPLVDAVYVKNFGRRKSWLVPTQYILGLFMIYLSTQVDRLLGNTDDRTPDVIALTVAFFLFEFLAATQDIAVDGW
ALTMLSRENVGYASTCNSVGQTAGYFLGNVLFLALESADFCNKYLRFQPQPRGIVTLSDFLFFWGTVFLITTTLVALLKKENEVSVVKEETQGITDTYKL
LFAIIKMPAVLTFCLLILTAKIGFSAADAVTGLKLVEEGVPKEHLALLAVPMVPLQIILPLIISKYTAGPQPLNTFYKAMPYRLLLGLEYALLVWWTPKV
EHQGGFPIYYYIVVLLSYALHQVTVYSMYVSIMAFNAKVSDPLIGGTYMTLLNTVSNLGGNWPSTVALWLVDPLTVKECVGASNQNCRTPDAVELCKKLG
GSCVTALDGYYVESIICVFIGFGWWFFLGPKFKKLQDEGSSSWKCKRNN
 
acetyl-coenzyme A transporter 1
Refseq ID:NP_004724
Protein GI:4757708
UniProt ID:O00400
mRNA ID:NM_004733
Length:549
RefSeq Status:REVIEWED
Protein sequence is identical to GI:300360496 (mRNA isoform)