LMPD Database

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LMP003154

Record overview

LMPD IDLMP003154
Gene ID80142
SpeciesHomo sapiens (Human)
Gene Nameprostaglandin E synthase 2
Gene SymbolPTGES2
SynonymsC9orf15; GBF-1; GBF1; PGES2; mPGES-2
Chromosome9
Map Location9q34.11
SummaryThe protein encoded by this gene is a membrane-associated prostaglandin E synthase, which catalyzes the conversion of prostaglandin H2 to prostaglandin E2. This protein also has been shown to activate the transcription regulated by a gamma-interferon-activated transcription element (GATE). Multiple transcript variants have been found for this gene. [provided by RefSeq, Jun 2009]
OrthologsView orthologs and multiple alignments for PTGES2

Proteins

prostaglandin E synthase 2 isoform 1
Refseq ID:NP_079348
Protein GI:13376617
UniProt ID:Q9H7Z7
mRNA ID:NM_025072
Length:377
RefSeq Status:REVIEWED
MDPAARVVRALWPGGCALAWRLGGRPQPLLPTQSRAGFAGAAGGPSPVAAARKGSPRLLGAAALALGGALGLYHTARWHLRAQDLHAERSAAQLSLSSRL
QLTLYQYKTCPFCSKVRAFLDFHALPYQVVEVNPVRRAEIKFSSYRKVPILVAQEGESSQQLNDSSVIISALKTYLVSGQPLEEIITYYPAMKAVNEQGK
EVTEFGNKYWLMLNEKEAQQVYGGKEARTEEMKWRQWADDWLVHLISPNVYRTPTEALASFDYIVREGKFGAVEGAVAKYMGAAAMYLISKRLKSRHRLQ
DNVREDLYEAADKWVAAVGKDRPFMGGQKPNLADLAVYGVLRVMEGLDAFDDLMQHTHIQPWYLRVERAITEASPAH
 
prostaglandin E synthase 2 isoform 2
Refseq ID:NP_001243264
Protein GI:373251223
UniProt ID:Q9H7Z7
mRNA ID:NM_001256335
Length:186
RefSeq Status:REVIEWED
MKAVNEQGKEVTEFGNKYWLMLNEKEAQQVYGGKEARTEEMKWRQWADDWLVHLISPNVYRTPTEALASFDYIVREGKFGAVEGAVAKYMGAAAMYLISK
RLKSRHRLQDNVREDLYEAADKWVAAVGKDRPFMGGQKPNLADLAVYGVLRVMEGLDAFDDLMQHTHIQPWYLRVERAITEASPAH
 
prostaglandin E synthase 2 isoform 2
Refseq ID:NP_945176
Protein GI:40068469
UniProt ID:Q9H7Z7
mRNA ID:NM_198938
Length:186
RefSeq Status:REVIEWED
Protein sequence is identical to GI:373251223 (mRNA isoform)
 
mat_peptide: 88..377
product: Prostaglandin E synthase 2 truncated form. {ECO:0000250}
experiment: experimental evidence, no additional details recorded
note: propagated from UniProtKB/Swiss-Prot (Q9H7Z7.1)
calculated_mol_wt: 33108
peptide sequence: 
ERSAAQLSLSSRLQLTLYQYKTCPFCSKVRAFLDFHALPYQVVEVNPVRRAEIKFSSYRKVPILVAQEGESSQQLNDSSVIISALKTYLVSGQPLEEIIT
YYPAMKAVNEQGKEVTEFGNKYWLMLNEKEAQQVYGGKEARTEEMKWRQWADDWLVHLISPNVYRTPTEALASFDYIVREGKFGAVEGAVAKYMGAAAMY
LISKRLKSRHRLQDNVREDLYEAADKWVAAVGKDRPFMGGQKPNLADLAVYGVLRVMEGLDAFDDLMQHTHIQPWYLRVERAITEASPAH