LMPD Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
LMP002677

Record overview

LMPD IDLMP002677
Gene ID84647
SpeciesHomo sapiens (Human)
Gene Namephospholipase A2, group XIIB
Gene SymbolPLA2G12B
SynonymsGXIIB; GXIIIsPLA2; PLA2G13
Alternate namesgroup XIIB secretory phospholipase A2-like protein; sPLA2-GXIIB; phospholipase A2, group XIII; group XIII secreted phospholipase A2; group XIII secretory phospholipase A2-like protein
Chromosome10
Map Location10q22.1
SummaryPhospholipase A2 (PLA2) enzymes catalyze hydrolysis of glycolipids to release free fatty acids and lysophospholipids. PLA2G12B belongs to the PLA2 family, but it is catalytically inactive due to an amino acid change in its active site and has altered phospholipid-binding properties (Rouault et al., 2003 [PubMed 14516201]).[supplied by OMIM, Mar 2008]
OrthologsView orthologs and multiple alignments for PLA2G12B

Proteins

group XIIB secretory phospholipase A2-like protein precursor
Refseq ID:NP_115951
Protein GI:45505135
UniProt ID:Q9BX93
mRNA ID:NM_032562
Length:195
RefSeq Status:VALIDATED
MKLASGFLVLWLSLGGGLAQSDTSPDTEESYSDWGLRHLRGSFESVNSYFDSFLELLGGKNGVCQYRCRYGKAPMPRPGYKPQEPNGCGSYFLGLKVPES
MDLGIPAMTKCCNQLDVCYDTCGANKYRCDAKFRWCLHSICSDLKRSLGFVSKVEAACDSLVDTVFNTVWTLGCRPFMNSQRAACICAEEEKEEL
 
sig_peptide: 1..19
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 1933
peptide sequence: 
MKLASGFLVLWLSLGGGLA

mat_peptide: 20..195
product: Group XIIB secretory phospholipase A2-like protein
experiment: experimental evidence, no additional details recorded
note: propagated from UniProtKB/Swiss-Prot (Q9BX93.2)
calculated_mol_wt: 19744
peptide sequence: 
QSDTSPDTEESYSDWGLRHLRGSFESVNSYFDSFLELLGGKNGVCQYRCRYGKAPMPRPGYKPQEPNGCGSYFLGLKVPESMDLGIPAMTKCCNQLDVCY
DTCGANKYRCDAKFRWCLHSICSDLKRSLGFVSKVEAACDSLVDTVFNTVWTLGCRPFMNSQRAACICAEEEKEEL