LMPD Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
LMP001666

Record overview

LMPD IDLMP001666
Gene ID7357
SpeciesHomo sapiens (Human)
Gene NameUDP-glucose ceramide glucosyltransferase
Gene SymbolUGCG
SynonymsGCS; GLCT1
Alternate namesceramide glucosyltransferase; GLCT-1; glucosylceramide synthase; UDP-glucose:N-acylsphingosine D-glucosyltransferase
Chromosome9
Map Location9q31
EC Number2.4.1.80
SummaryGlycosphingolipids (GSLs) are a group of membrane components that contain lipid and sugar moieties. They are present in essentially all animal cells and are believed to have important roles in various cellular processes. UDP-glucose ceramide glucosyltransferase catalyzes the first glycosylation step in glycosphingolipid biosynthesis. The product, glucosylceramide, is the core structure of more than 300 GSLs. UGCG is widely expressed and transcription is upregulated during keratinocyte differentiation. [provided by RefSeq, Oct 2009]
OrthologsView orthologs and multiple alignments for UGCG

Proteins

ceramide glucosyltransferase
Refseq ID:NP_003349
Protein GI:4507811
UniProt ID:Q16739
mRNA ID:NM_003358
Length:394
RefSeq Status:REVIEWED
MALLDLALEGMAVFGFVLFLVLWLMHFMAIIYTRLHLNKKATDKQPYSKLPGVSLLKPLKGVDPNLINNLETFFELDYPKYEVLLCVQDHDDPAIDVCKK
LLGKYPNVDARLFIGGKKVGINPKINNLMPGYEVAKYDLIWICDSGIRVIPDTLTDMVNQMTEKVGLVHGLPYVADRQGFAATLEQVYFGTSHPRYYISA
NVTGFKCVTGMSCLMRKDVLDQAGGLIAFAQYIAEDYFMAKAIADRGWRFAMSTQVAMQNSGSYSISQFQSRMIRWTKLRINMLPATIICEPISECFVAS
LIIGWAAHHVFRWDIMVFFMCHCLAWFIFDYIQLRGVQGGTLCFSKLDYAVAWFIRESMTIYIFLSALWDPTISWRTGRYRLRCGGTAEEILDV