LMPD Database

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LMP001261

Record overview

LMPD IDLMP001261
Gene ID91012
SpeciesHomo sapiens (Human)
Gene Nameceramide synthase 5
Gene SymbolCERS5
SynonymsLASS5; Trh4
Alternate namesceramide synthase 5; LAG1 homolog, ceramide synthase 5; LAG1 longevity assurance homolog 5
Chromosome12
Map Location12q13.12
EC Number2.3.1.24
SummaryThis gene encodes a protein that belongs to the TLC (TRAM, LAG1 and CLN8 homology domains) family of proteins. The encoded protein functions in the synthesis of ceramide, a lipid molecule that is involved in a several cellular signaling pathways. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
OrthologsView orthologs and multiple alignments for CERS5

Proteins

ceramide synthase 5 isoform 1
Refseq ID:NP_671723
Protein GI:22218345
UniProt ID:Q8N5B7
mRNA ID:NM_147190
Length:392
RefSeq Status:REVIEWED
MATAAQGPLSLLWGWLWSERFWLPENVSWADLEGPADGYGYPRGRHILSVFPLAAGIFFVRLLFERFIAKPCALCIGIEDSGPYQAQPNAILEKVFISIT
KYPDKKRLEGLSKQLDWNVRKIQCWFRHRRNQDKPPTLTKFCESMWRFTFYLCIFCYGIRFLWSSPWFWDIRQCWHNYPFQPLSSGLYHYYIMELAFYWS
LMFSQFTDIKRKDFLIMFVHHLVTIGLISFSYINNMVRVGTLIMCLHDVSDFLLEAAKLANYAKYQRLCDTLFVIFSAVFMVTRLGIYPFWILNTTLFES
WEIIGPYASWWLLNGLLLTLQLLHVIWSYLIARIALKALIRGKVSKDDRSDVESSSEEEDVTTCTKSPCDSSSSNGANRVNGHMGGSYWAEE
 
ceramide synthase 5 isoform 2
Refseq ID:NP_001268660
Protein GI:528881078
UniProt ID:Q8N5B7
mRNA ID:NM_001281731
Length:334
RefSeq Status:REVIEWED
MMKPRPKRFIAKPCALCIGIEDSGPYQAQPNAILEKVFISITKYPDKKRLEGLSKQLDWNVRKIQCWFRHRRNQDKPPTLTKFCESMWRFTFYLCIFCYG
IRFLWSSPWFWDIRQCWHNYPFQPLSSGLYHYYIMELAFYWSLMFSQFTDIKRKDFLIMFVHHLVTIGLISFSYINNMVRVGTLIMCLHDVSDFLLEAAK
LANYAKYQRLCDTLFVIFSAVFMVTRLGIYPFWILNTTLFESWEIIGPYASWWLLNGLLLTLQLLHVIWSYLIARIALKALIRGKVSKDDRSDVESSSEE
EDVTTCTKSPCDSSSSNGANRVNGHMGGSYWAEE