LMPD Database

LMP000994

Record overview

LMPD IDLMP000994
Gene ID6482
SpeciesHomo sapiens (Human)
Gene NameST3 beta-galactoside alpha-2,3-sialyltransferase 1
Gene SymbolST3GAL1
SynonymsGal-NAc6S; SIAT4A; SIATFL; ST3GalA; ST3GalA.1; ST3GalIA; ST3GalIA,1; ST3O
Alternate namesCMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1; SIAT4-A; ST3GalI; alpha 2,3-ST 1; beta-galactoside alpha-2,3-sialyltransferase 1; Gal-beta-1,3-GalNAc-alpha-2,3-sialyltransferase; sialyltransferase 4A (beta-galactoside alpha-2,3-sialytransferase); sialyltransferase 4A (beta-galactoside alpha-2,3-sialyltransferase); sialyltransferase 4A (beta-galactosidase alpha-2,3-sialytransferase)
Chromosome8
Map Location8q24.22
EC Number2.4.99.4
SummaryThe protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The encoded protein is normally found in the Golgi but can be proteolytically processed to a soluble form. Correct glycosylation of the encoded protein may be critical to its sialyltransferase activity. This protein, which is a member of glycosyltransferase family 29, can use the same acceptor substrates as does sialyltransferase 4B. Two transcript variants encoding the same protein have been found for this gene. Other transcript variants may exist, but have not been fully characterized yet. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for ST3GAL1

Proteins

CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1
Refseq ID:NP_775479
Protein GI:27765096
UniProt ID:Q11201
mRNA ID:NM_173344
Length:340
RefSeq Status:REVIEWED
MVTLRKRTLKVLTFLVLFIFLTSFFLNYSHTMVATTWFPKQMVLELSENLKRLIKHRPCTCTHCIGQRKLSAWFDERFNQTMQPLLTAQNALLEDDTYRW
WLRLQREKKPNNLNDTIKELFRVVPGNVDPMLEKRSVGCRRCAVVGNSGNLRESSYGPEIDSHDFVLRMNKAPTAGFEADVGTKTTHHLVYPESFRELGD
NVSMILVPFKTIDLEWVVSAITTGTISHTYIPVPAKIRVKQDKILIYHPAFIKYVFDNWLQGHGRYPSTGILSVIFSMHVCDEVDLYGFGADSKGNWHHY
WENNPSAGAFRKTGVHDADFESNVTATLASINKIRIFKGR
 
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1
Refseq ID:NP_003024
Protein GI:4506951
UniProt ID:Q11201
mRNA ID:NM_003033
Length:340
RefSeq Status:REVIEWED
Protein sequence is identical to GI:27765096 (mRNA isoform)