LMPD Database

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LMP000194

Record overview

LMPD IDLMP000194
Gene ID4759
SpeciesHomo sapiens (Human)
Gene Namesialidase 2 (cytosolic sialidase)
Gene SymbolNEU2
SynonymsSIAL2
Alternate namessialidase-2; neuraminidase 2; cytosolic sialidase; N-acetyl-alpha-neuraminidase 2
Chromosome2
Map Location2q37
EC Number3.2.1.18
SummaryThis gene belongs to a family of glycohydrolytic enzymes which remove sialic acid residues from glycoproteins and glycolipids. Expression studies in COS7 cells confirmed that this gene encodes a functional sialidase. Its cytosolic localization was demonstrated by cell fractionation experiments. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for NEU2

Proteins

sialidase-2
Refseq ID:NP_005374
Protein GI:222352170
UniProt ID:Q9Y3R4
mRNA ID:NM_005383
Length:380
RefSeq Status:REVIEWED
MASLPVLQKESVFQSGAHAYRIPALLYLPGQQSLLAFAEQRASKKDEHAELIVLRRGDYDAPTHQVQWQAQEVVAQARLDGHRSMNPCPLYDAQTGTLFL
FFIAIPGQVTEQQQLQTRANVTRLCQVTSTDHGRTWSSPRDLTDAAIGPAYREWSTFAVGPGHCLQLHDRARSLVVPAYAYRKLHPIQRPIPSAFCFLSH
DHGRTWARGHFVAQDTLECQVAEVETGEQRVVTLNARSHLRARVQAQSTNDGLDFQESQLVKKLVEPPPQGCQGSVISFPSPRSGPGSPAQWLLYTHPTH
SWQRADLGAYLNPRPPAPEAWSEPVLLAKGSCAYSDLQSMGTGPDGSPLFGCLYEANDYEEIVFLMFTLKQAFPAEYLPQ